I started with CFE powder and then finally went with TiteGroup powder. This is what I ended up with:
The CFE for me was not as good as the titegroup powder I reloaded with this time for my 45. My EDC is the Colt Combat Commander 4.25" barrel. Formula for my Best load to date: Everglades 230 gn FMJ round nose, 4.2 gn of TiteGroup, COL of 1.248, Primers Fed or Win large (both worked ok, but I prefer the Federal). I saw no difference in the various brass that I had. I did a slow load on my Dillon Press to verify everything (powder and seatings of primer and bullet and tolerances) on EACH AND EVERY round. This was so good for my specific EDC, I doubt I will change my formula.
Difference in CFE and Titegroup Powder was about 2" for titegroup vs 6" for CFE groupings at 25 yds. My previous FMJ round nose was seated at 1.265 and used CFE of various volumes of between 6.0gn to 6.8gn and I could never achieve even close to what my current formula gives. Also the reduction in kick is very noticeable, (as President Trump says: Bigley).
Jim