Recently went to the range with a buddy who had some meprolights on his Gen 3 19. After about a 100 rounds he shot the front sight loose. It had no threadlocker on it. Apparently he had the sights installed when he purchased the pistol, and told me he witnessed the guy who did it apply blue threadlocker to the rear sight during installation, but didn't see any applied to the front sight.
That said, is it an absolute necessity to have threadlocker on your sights, especially with the screw in variety like Glocks? Or was this just an instance where the front sight might not have been screwed in tightly enough?